1186654-76-1 Usage
General Description
Tert-butyl (3S,4R)-3-(hydroxymethyl)-4-(4-methoxyphenyl)pyrrolidine-1-carboxylate is a chemical compound that is derived from a pyrrolidine-based structure. It consists of a tert-butyl group attached to a pyrrolidine ring, which in turn is substituted with a hydroxymethyl group and a 4-methoxyphenyl group. tert-butyl (3S,4R)-3-(hydroxymethyl)-4-(4-methoxyphenyl)pyrrolidine-1-carboxylate has a stereochemical configuration of 3S,4R, indicating the positions of the substituents in relation to each other. It may have potential pharmacological and medicinal applications due to its structural features and its ability to modulate biological processes. Further research and evaluation are necessary to determine the full range of its properties and potential applications.
Check Digit Verification of cas no
The CAS Registry Mumber 1186654-76-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,6,5 and 4 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1186654-76:
(9*1)+(8*1)+(7*8)+(6*6)+(5*6)+(4*5)+(3*4)+(2*7)+(1*6)=191
191 % 10 = 1
So 1186654-76-1 is a valid CAS Registry Number.
1186654-76-1Relevant articles and documents
Regio- and Stereoselective Palladium-Catalyzed C(sp3)-H Arylation of Pyrrolidines and Piperidines with C(3) Directing Groups
Antermite, Daniele,Affron, Dominic P.,Bull, James A.
, p. 3948 - 3952 (2018)
The selective synthesis of cis-3,4-disubstituted pyrrolidines and piperidines is achieved by a Pd-catalyzed C-H arylation with excellent regio- and stereoselectivity using an aminoquinoline auxiliary at C(3). The arylation conditions are silver free, use a low catalyst loading, and employ inexpensive K2CO3 as a base. Directing group removal is accomplished under new, mild conditions to access amide-, acid-, ester-, and alcohol-containing fragments and building blocks. This C-H arylation protocol enabled a short and stereocontrolled formal synthesis of (-)-paroxetine.
