1186663-18-2 Usage
Uses
Used in Pharmaceutical Synthesis:
1-(2,4-Difluorophenyl)cyclopropylamine Hydrochloride is used as a key intermediate in the synthesis of various pharmaceutical compounds for its ability to contribute to the development of new drugs with improved efficacy and safety profiles.
Used in Chemical Research:
In the field of chemical research, 1-(2,4-Difluorophenyl)cyclopropylamine Hydrochloride is utilized as a valuable compound for studying the effects of fluorination on the properties and reactivity of cyclopropylamines, which can lead to advancements in organic chemistry and medicinal chemistry.
Used in Drug Development:
1-(2,4-Difluorophenyl)cyclopropylamine Hydrochloride is employed in drug development for its potential therapeutic properties, which can be explored and optimized for the treatment of various medical conditions, enhancing the repertoire of available pharmaceuticals for patient care.
Used in Medicinal Chemistry:
In the industry of medicinal chemistry, 1-(2,4-Difluorophenyl)cyclopropylamine Hydrochloride is used as a building block for designing and optimizing new drug candidates, leveraging its unique structural features to improve pharmacokinetics, selectivity, and potency of the resulting compounds.
Check Digit Verification of cas no
The CAS Registry Mumber 1186663-18-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,6,6,6 and 3 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1186663-18:
(9*1)+(8*1)+(7*8)+(6*6)+(5*6)+(4*6)+(3*3)+(2*1)+(1*8)=182
182 % 10 = 2
So 1186663-18-2 is a valid CAS Registry Number.
1186663-18-2Relevant academic research and scientific papers
Oxadiazole Amine Derivative Compounds as Histone Deacetylase 6 Inhibitor, and the Pharmaceutical Composition Comprising the same
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Paragraph 1896-1899, (2017/07/18)
The present invention relates to a novel compound having an activity of inhibiting histone deacetylase 6 (HDAC6), an optical isomer thereof or a pharmaceutically acceptable salt thereof, a use thereof for preparation of a drug for treatment, a pharmaceutical composition comprising the same, a treatment method using the composition, and a method for preparing the same. The novel compound, an optical isomer thereof or a pharmaceutically acceptable salt thereof according to the present invention has an activity of inhibiting histone deacetylase 6 (HDAC6), and is effective for preventing or treating HDAC6-related diseases, including infectious diseases; neoplasm; endocrine, nutritional and metabolic diseases; mental and behavior disorders; nerve disorders; eye and adnexa diseases; cardiovascular diseases; respiratory diseases; digestive organ diseases; skin and subcutaneous tissue diseases; musculoskeletal and connective tissue diseases; or congenital malformation, deformation and chromosomal abnormality.COPYRIGHT KIPO 2017
