118678-22-1

Basic information

• Product Name: C₁₃H₁₄O₅
• Synonyms: C₁₃H₁₄O₅
• CAS NO: 118678-22-1
• Molecular Weight: 250.251
• Mol File: 118678-22-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₃H₁₄O₅(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₃H₁₄O₅(118678-22-1)
• EPA Substance Registry System: C₁₃H₁₄O₅(118678-22-1)

Safety Data

• Hazardous Substances Data: 118678-22-1(Hazardous Substances Data)

Upstream product

• 14737-91-8 (Z)-o-methoxycinnamic acid 
• 541-41-3 chloroformic acid ethyl ester 

Downstream Products

• 118653-15-9 (Z)-3-(2-methoxyphenyl)prop-2-enamide 

Relevant articles and documents

Synthesis of Enamides

(Z)-3-Arylprop-2-enoic acids can be converted by the Curtius procedure, through the acyl azides, into (Z)-2-arylethenyl isocyanates, which with methanol give methyl (Z)-N-(2-arylethenyl)carbamates.Acylation of the (Z)-enecarbamates, through their anions, leads to methyl (Z)-N-acyl-N-(2-arylethenyl)carbamates, which on treatment with lithium iodide in boiling N,N-dimethylformamide or acetonitrile undergo demethoxycarbonylation to give (Z)-enamides.The stereospecific route to enamides can also be used in the E-series.Treatment of (Z)- or (E)-2-arylethenyl isocyanates with trifluoroacetic acid gives (E)-N-(2-arylethenyl)trifluoroacetamides,the anions of which, with acylating agents, give (E)-enamides directly.