118712-89-3

Basic information

• Product Name: Transfluthrin
• Synonyms: TRANSFLUTHRIN;3-(2,2-dichloroethenyl)-2,2-dimethyl-cyclopropanecarboxylic acid (2,3,5,6-tetrafluorophenyl)methylester;2,3,5,6-tetrafluorobenzyl-(1r,s)-trans-3-(2,2-dichlorovinyl)-2, 2-dimethyl-cyclopropanecarboxylate;BAYGON;BAYOTHRIN;TRANSFUTHRIN PESTANAL, 250 MG;Cyclopropanecarboxylic acid, 3-(2,2-dichloroethenyl)-2,2-dimethyl-, (2,3,5,6-tetrafluorophenyl)methyl ester, (1R,3S)-;2,3,5,6-tetrafluorobenzyl trans-2-(2,2-dichlorovinyl)-3,3-dimethylcyclopropanecarboxylate
• CAS NO: 118712-89-3
• Molecular Formula: C₁₅H₁₂Cl₂F₄O₂
• Molecular Weight: 371.16
• EINECS: 405-060-5
• Product Categories: Alpha sort;Insecticides;Pesticides;PyrethroidsPesticides&Metabolites;Q-ZAlphabetic;TP - TZ
• Mol File: 118712-89-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 32 °C
• Boiling Point: 351.4 °C at 760 mmHg
• Flash Point: >35 °C
• Appearance: colorless crystals
• Density: 1.492 g/cm³
• Vapor Pressure: 4.12E-05mmHg at 25°C
• Refractive Index: 1.549
• CAS DataBase Reference: Transfluthrin(CAS DataBase Reference)
• NIST Chemistry Reference: Transfluthrin(118712-89-3)
• EPA Substance Registry System: Transfluthrin(118712-89-3)

Safety Data

• Hazard Codes: Xi;N,N,Xi
• Statements: 38-50/53
• Safety Statements: 36/37-60-61
• RIDADR: UN 3077
• WGK Germany: 2
• Hazardous Substances Data: 118712-89-3(Hazardous Substances Data)

Usage

Uses

Transfluthrin is a fluorinated aromatic compound for proteomics research.

Definition

ChEBI: A carboxylic ester obtained by formal condensation of 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid and 2,3,5,6-tetrafluorobenzyl alcohol.

InChI:InChI=1/C15H12Cl2F4O2/c1-15(2)7(3-10(16)17)11(15)14(22)23-5-6-12(20)8(18)4-9(19)13(6)21/h3-4,7,11H,5H2,1-2H3/t7-,11+/m1/s1

Synthetic route

(1R)-trans-3-(2,2-dichloro-1-ethenyl)-2,2-dimethylcyclopropanecarboxylic acid chloride (61914-47-4) + (2,3,5,6-tetrafluorophenyl)methanol (4084-38-2) → transfluthrin (118712-89-3)

Conditions	Yield
With pyridine In toluene at 5 - 15℃; for 3h;	97.6%

Upstream product

• 61914-47-4 (1R)-trans-3-(2,2-dichloro-1-ethenyl)-2,2-dimethylcyclopropanecarboxylic acid chloride 
• 4084-38-2 (2,3,5,6-tetrafluorophenyl)methanol 

Relevant articles and documents

IMPROVED PROCESS FOR THE PREPARATION OF PYRETHROIDS

The present disclosure concerns a process for preparing a pyrethroid, said process comprising the steps of: a) reacting an acid chloride with an alcohol in a suitable organic solvent and in the presence of a nitrogen acid acceptor in a temperature range from 0°C to 40°C; and b) washing with water and/or an aqueous basic solution, wherein a suitable amount of a polyamine (W) H2N-(CH2)b-Ae-[(CH2)c-A-]p-(CH2)d-NH2, where A is -NH- or -O-, b and d are independently an integer in the range of 1 -5, c is an integer in the range of 2-5, e is an integer from 0 to 1, p is an integer in the range of 0-5, is added in step a) or b) or after step a) and before step b).