1187166-16-0Relevant articles and documents
Iron-catalyzed cascade reaction of ynone with o-aminoaryl compounds: A Michael addition-cyclization approach to 3-carbonyl quinolines
Li, Hongfeng,Xu, Xiaolei,Yang, Jingyu,Xie, Xin,Huang, He,Li, Yanzhong
supporting information; experimental part, p. 530 - 533 (2011/02/28)
An efficient iron-catalyzed cascade Michael addition-cyclization of o-aminoaryl compounds including o-aminoaryl aldehydes, o-aminoaryl ketones, and o-aminobenzyl alcohols with ynones for the synthesis of 3-carbonyl quinolines is reported. The reactions proceed to afford 3-carbonyl quinoline derivatives with or without substituent at the C-4 position in good to high yields using Iron(III) chloride hexahydrate as the catalyst in the air.