1187182-28-0

Basic information

• Product Name: {(E)-1-[2-(1,3-dioxan-2-yl)phenyl]methylidene}-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]amine
• Synonyms: {(E)-1-[2-(1,3-dioxan-2-yl)phenyl]methylidene}-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]amine
• CAS NO: 1187182-28-0
• Molecular Weight: 304.389
• Mol File: 1187182-28-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: {(E)-1-[2-(1,3-dioxan-2-yl)phenyl]methylidene}-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]amine(CAS DataBase Reference)
• NIST Chemistry Reference: {(E)-1-[2-(1,3-dioxan-2-yl)phenyl]methylidene}-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]amine(1187182-28-0)
• EPA Substance Registry System: {(E)-1-[2-(1,3-dioxan-2-yl)phenyl]methylidene}-[(S)-2-(methoxymethyl)pyrrolidin-1-yl]amine(1187182-28-0)

Safety Data

• Hazardous Substances Data: 1187182-28-0(Hazardous Substances Data)

Upstream product

• 139086-86-5 2-(1,3-dioxan-2-yl)benzaldehyde 
• 59983-39-0 (S)-1-amino-2-(methoxymethyl)pyrrolidine 

Relevant articles and documents

First asymmetric synthesis of (Un)saturated 1-Alkylbenzo[c]azepin-3-ones: Extension to the corresponding benzazeplnes

A flexible route for the stereoselective synthesis of a variety of structurally diverse (1R)-1-alkyldihydro and tetrahydro-benzazepin(ones) has been developed. The key step is a highly diastereoselective 1,2-addition process applied to a stereopure aromatic hydrazone combined with a ring-closing metathesis reaction to secure the formation of the seven-membered azaheterocycle ring system.