1187225-42-8Relevant articles and documents
Inhibitors of VIM-2 by screening pharmacologically active and click-chemistry compound libraries
Minond, Dmitriy,Saldanha, S. Adrian,Subramaniam, Prem,Spaargaren, Michael,Spicer, Timothy,Fotsing, Joseph R.,Weide, Timo,Fokin, Valery V.,Sharpless, K. Barry,Galleni, Moreno,Bebrone, Carine,Lassaux, Patricia,Hodder, Peter
experimental part, p. 5027 - 5037 (2009/12/04)
VIM-2 is an Ambler class B metallo-β-lactamase (MBL) capable of hydrolyzing a broad-spectrum of β-lactam antibiotics. Although the discovery and development of MBL inhibitors continue to be an area of active research, an array of potent, small molecule in