1187235-18-2Relevant academic research and scientific papers
Efficient synthesis of carbazoles via PtCl2-catalyzed RT cyclization of 1-(indol-2-yl)-2,3-allenols: Scope and mechanism
Kong, Wangqing,Fu, Chunling,Ma, Shengming
experimental part, p. 2164 - 2173 (2012/04/11)
A detailed study on the scope of the efficient PtCl2-catalyzed synthesis of carbazoles from 1-(indol-2-yl)-2,3-allenols is described. Through isotopic labeling experiments, it is confirmed that the reaction proceeds through a unique metal carbene intermediate, which undergoes subsequent highly selective 1,2-hydrogen migration to afford carbazoles. The reaction shows wide scope and allows the introduction of a variety of different substituents at different positions on the carbazole due to the substituent-loading capability of both indole and the allene moiety.
An efficient synthesis of carbazoles from PtCl2-catalyzed cyclization of 1-(indol-2-yl)-2,3-allenols
Kong, Wangqing,Fu, Chunling,Ma, Shengming
supporting information; experimental part, p. 4572 - 4574 (2009/12/28)
The PtCl2-catalyzed reaction of 1-(indol-2-yl)-2,3-allenols occurred smoothly to form carbazoles by connecting the 3-carbon atom of indole with the 4-carbon atom of the allenol moiety, referring to the carbon atom connected to the hydroxyl grou
