1187341-91-8Relevant academic research and scientific papers
Discovery of selective 2,4-diaminopyrimidine-based photoaffinity probes for glyoxalase i
Zhou, Yiqing,Guo, Tianlin,Li, Xitao,Dong, Yi,Galatsis, Paul,Johnson, Douglas S.,Pan, Zhengying
, p. 352 - 357 (2014)
Glyoxalase I (GLO-1) plays a critical role in the detoxification of 2-oxoaldehydes and is highly expressed in cancer cells. Through photo-affinity labelling and affinity pull-down approaches, a series of 2,4-diaminopyrimidine compounds were discovered to
SULFONAMIDES AS ZAP-70 INHIBITORS
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Page/Page column 74, (2009/10/22)
The invention relates to compounds of formula (I), wherein R1 to R9 and R4a have the meaning as cited in the description and the claims. Said compounds are useful as inhibitors of ZAP-70 for the treatment or prophylaxis of
USE OF LRRK2 INHIBITORS FOR NEURODEGENERATIVE DISEASES
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Page/Page column 34, (2009/12/02)
The invention relates to compounds of formula (I), wherein R1 to R9 and R4a have the meaning as cited in the description and the claims for use in a for use in a method of treating or preventing diseases and disorders asso
