1187364-07-3Relevant academic research and scientific papers
Iridium-catalyzed oxidative olefination of furans with unactivated alkenes
Sevov, Christo S.,Hartwig, John F.
supporting information, p. 10625 - 10631 (2014/08/18)
The oxidative coupling of arenes and alkenes is an attractive strategy for the synthesis of vinylarenes, but reactions with unactivated alkenes have typically occurred in low yield. We report an Ir-catalyzed oxidative coupling of furans with unactivated olefins to generate branched vinylfuran products in high yields and with high selectivities with a second alkene as the hydrogen acceptor. Detailed mechanistic experiments revealed catalyst decomposition pathways that were alleviated by the judicious selection of reaction conditions and application of new ligands.
Palladium-catalyzed dehydrogenative coupling of furans with styrenes
Aouf, Chahinez,Thiery, Emilie,Le Bras, Jean,Muzart, Jacques
supporting information; experimental part, p. 4096 - 4099 (2009/12/06)
Under palladium(II)-catalyzed and oxidative conditions, the coupling of furans with styrenes leads to the formation of Heck-type products In medium to good yields. The reaction Is highly regio- and stereoselective, giving frans-olefins predominantly.
