1187388-15-3

Upstream product

• 1187388-07-3 4-(4-formylphenyl)-4-hydroxybut-2-ynoic acid 
• 52010-97-6 4-(hydroxylmethyl)benzaldehyde 
• 623-27-8 terephthalaldehyde, 

Downstream Products

• 352233-12-6 1-[4-(hydroxymethyl)phenyl]propan-1-one 

Relevant academic research and scientific papers

Chemoselective reduction of aldehydes: Via a combination of NaBH4 and acetylacetone

A bench-stable combination of NaBH4-acetylacetone was developed for the efficient chemoselective reduction of aldehydes in the presence of ketones. This method offers a useful synthetic protocol for distinguishing carbonyl reaction sites, and its synthetic utility is reflected by its moisture tolerance and high efficiency in a variety of complex settings.

Catalytic decarboxylation of 2-alkynoic acids

(Chemical Equation Presented) A very efficient protocol enabling catalytic decarboxylation of a wide range of 2-alkynoic acids is described. The reaction conditions and the scope of the process are examined. The method is further utilized in a model decar