118741-90-5

Upstream product

• 10160-87-9 Propiolaldehyde diethyl acetal 
• 118779-14-9 N-methoxy-N-methyl-3,4,5-trimethoxybenzamide 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 4521-61-3 3,4,5-Trimethoxybenzoyl chloride 

Downstream Products

• 84386-11-8 (E)-4-(3,4,5-trimethoxyphenyl)-4-oxo-2-butenoic acid 

Relevant academic research and scientific papers

A New Method for the Preparation of (E)-3-Acylprop-2-enoic Acids

A new method for the preparation of (E)-3-acylprop-2-enoic acids ( = (E)-3-acylacrylic acids) of type II via acid catalyzed isomerization of the corresponding 3-acylprop-2-ynal acetals of type I (Scheme 1) has been found.The described reaction gives a rap

Propiolophenone derivatives

Propiolophenone derivatives of the formula STR1 wherein R6 is hydrogen, lower alkyl or a group of the formula STR2 as well as corresponding hydroxy compounds of the formula STR3 wherein R6' is hydrogen, lower alkyl, a group of formula (a), (b), (c), (d) or (e) or a group of the formula exhibit mucosa-protective and/or gastric acid secretion-inhibiting properties, such that they can be used for the control or prevention of illnesses of the gastrointestinal tract, especially against gastric ulcers and/or duodenal ulcers.