118744-88-0

Basic information

• Product Name: 1-[(2R,5S)-5-(hydroxymethyl)-4-methyl-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione
• Synonyms: Thymidine, 3'-deoxy-2',3'-didehydro-3'-methyl-
• CAS NO: 118744-88-0
• Molecular Formula: C₁₁H₁₄N₂O₄
• Molecular Weight: 238.2399
• Mol File: 118744-88-0.mol
• Article Data: 2

Chemical Properties

• Density: 1.315g/cm³
• Refractive Index: 1.56
• CAS DataBase Reference: 1-[(2R,5S)-5-(hydroxymethyl)-4-methyl-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[(2R,5S)-5-(hydroxymethyl)-4-methyl-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(118744-88-0)
• EPA Substance Registry System: 1-[(2R,5S)-5-(hydroxymethyl)-4-methyl-2,5-dihydrofuran-2-yl]-5-methylpyrimidine-2,4(1H,3H)-dione(118744-88-0)

Safety Data

• Hazardous Substances Data: 118744-88-0(Hazardous Substances Data)

Usage

Chemical structure

The compound consists of a pyrimidine ring with a furan ring attached to it.

Stereochemistry

The furan ring has a 2R,5S configuration, indicating the specific arrangement of atoms in the molecule.

Functional groups

The furan ring contains a hydroxymethyl group (-CH2OH) and a methyl group (-CH3). The pyrimidine ring also contains a methyl group at the 5-position.

Potential applications

The compound has potential biological activity and may be of interest for pharmaceutical or research purposes.

Unique structure

The combination of the pyrimidine and furan rings, along with the functional groups, gives the molecule a unique structure.

Further exploration

The compound's unique structure and combination of functional groups make it a potentially valuable molecule for further exploration and study.

Tautomeric forms

The compound may exist in different tautomeric forms, which could have different properties and reactivities.

Solubility

The solubility of the compound in various solvents (e.g., water, organic solvents) may be an important factor to consider for its potential applications.

Stability

The compound's stability under different conditions (e.g., temperature, pH, light exposure) may affect its suitability for various applications.

Synthesis

The synthesis of the compound may involve multiple steps and require specific reagents or conditions, which could impact its availability and cost.

Upstream product

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• 130411-34-6 methyl-5-O-benzoyl-3-C-methyl-2-deoxy-α-D-threo-pentofuranoside 

Relevant articles and documents

3'-C-branched 2'-deoxy-5-methyluridines: Synthesis, enzyme inhibition, and antiviral properties

A synthesis scheme for 3'-C-methyl-2'-deoxynucleosides and 3'-C- methylidene-2',3'-dideoxy-5-methyluridine has been proposed with 2- deoxyribose as the starting material. Methyl 5-O-benzoyl-2-deoxyribofuranose was oxidized and the mixture of the 3'-keto d