1187575-80-9Relevant academic research and scientific papers
Synthesis and small-animal positron emission tomography evaluation of [11C]-elacridar as a radiotracer to assess the distribution of P-glycoprotein at the blood-brain barrier
D?rner, Bernd,Kuntner, Claudia,Bankstahl, Jens P.,Bankstahl, Marion,Stanek, Johann,Wanek, Thomas,Stundner, Gloria,Mairinger, Severin,L?scher, Wolfgang,Müller, Markus,Langer, Oliver,Erker, Thomas
experimental part, p. 6073 - 6082 (2010/03/24)
With the aim to develop a positron emission tomography (PET) tracer to assess the distribution of P-glycoprotein (P-gp) at the blood-brain barrier (BBB) in vivo, the potent third-generation P-gp inhibitor elacridar (1) was labeled with 11C by r
