1187618-41-2

Upstream product

• 1187618-40-1 (1S,5S)-3-[(E)-(S)-6-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-hex-2-enoyl]-1,5-bis-methoxymethoxy-2,2,4-trimethyl-cyclohex-3-enecarbaldehyde 
• 4301-14-8 acetylenemagnesium bromide 

Downstream Products

• 1187618-42-3 (E)-(S)-1-((3S,5S)-3,5-bis-methoxymethoxy-2,6,6-trimethyl-5-propynoyl-cyclohex-1-enyl)-6-(tert-butyl-dimethyl-silanyloxy)-4-(4-methoxy-benzyloxy)-hex-2-en-1-one 

Relevant academic research and scientific papers

Synthesis of a tetraoxy-bis-nortaxadiene, en route to taxol, using a cascade radical cyclisation sequence

Concise syntheses of the substituted enynediones 28a, 33b and 36 starting from the cyclohexenealdehyde 18, corresponding to ring A in the taxanes, and the vinylstannane 24, are described. Treatment of 36 with Bu3SnH-AIBN did not lead to the oxy