1187643-27-1Relevant academic research and scientific papers
Formation of novel 1,3-thiazole- and 1,2-thiazole-fused aporphines and study on the simultaneously occurring benzothiazole-benzisothiazole-type isomerization
Sipos, Attila,Berenyi, Sandor
experimental part, p. 387 - 396 (2010/06/16)
The synthesis and acid-catalyzed rearrangement of novel thiazolomorphinandienes have been presented. An isomerization was observed simultaneously with the backbone transformation. An extensive study was performed to determine the major effects of the isom
Synthesis and pharmacological evaluation of thiazole and isothiazole derived apomorphines
Sipos, Attila,Mueller, Franziska K. U.,Lehmann, Jochen,Berenyi, Sandor,Antus, Sandor
experimental part, p. 557 - 568 (2009/12/25)
We have presented the synthesis of novel thiazolo- and isothiazolo- apomorphines 12-17 resulting - in part - from an unexpected isomerization step occurred during the acid-catalyzed rearrangement of precursor thiazolo-morphinandienes 3-5. These 2,3-disubs
