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1187830-79-0

5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride, also known as taltirelin or TA-0910, is a non-peptide thyrotropin-releasing hormone (TRH) analogue with a complex heterocyclic structure. As a hydrochloride salt derivative of 5,6,7,8-tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one, this organic compound is utilized in scientific research and pharmaceutical applications. Its unique molecular structure and potential biological activities have garnered interest among researchers in the fields of drug development and neurological disorders.

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  • 1187830-79-0 Structure

  • Basic information

    1. Product Name: 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride
    2. Synonyms:
    3. CAS NO:1187830-79-0
    4. Molecular Formula: C7H9N3O*ClH
    5. Molecular Weight: 187.6268
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1187830-79-0.mol

  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: Sealed in dry,Room Temperature
    8. Solubility: N/A
    9. CAS DataBase Reference: 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride(CAS DataBase Reference)
    10. NIST Chemistry Reference: 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride(1187830-79-0)
    11. EPA Substance Registry System: 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride(1187830-79-0)

  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1187830-79-0(Hazardous Substances Data)

1187830-79-0 Usage

Uses

Used in Pharmaceutical Applications:
5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride is used as a TRH analogue for its potential therapeutic effects in treating neurological disorders. Its non-peptide nature may offer advantages over peptide-based TRH agonists, such as improved stability and bioavailability.
Used in Scientific Research:
In the field of scientific research, 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride serves as a valuable tool for studying the mechanisms of action and potential applications of TRH agonists. Its unique molecular structure allows researchers to investigate its interactions with TRH receptors and explore its role in modulating various physiological processes.
Used in Drug Development:
5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride is utilized in drug development as a lead compound for the design and synthesis of novel TRH agonists. Its non-peptide nature and potential biological activities make it an attractive candidate for the development of new therapeutic agents targeting neurological disorders.
Used in Neurological Disorders Treatment:
In the treatment of neurological disorders, 5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride is used as a TRH agonist for its potential to modulate neurotransmitter release and influence neuronal activity. Its ability to cross the blood-brain barrier and interact with TRH receptors may contribute to its therapeutic effects in conditions such as Parkinson's disease, Alzheimer's disease, and other neurodegenerative disorders.
Used in Neurotransmission Modulation:
5,6,7,8-Tetrahydropyrido[4,3-d]pyriMidin-4(3H)-one hydrochloride is employed as a modulator of neurotransmission for its potential to enhance the release of neurotransmitters such as dopamine, norepinephrine, and serotonin. This property may contribute to its therapeutic effects in treating various neurological and psychiatric conditions, including depression, anxiety, and cognitive impairments.

Check Digit Verification of cas no

The CAS Registry Mumber 1187830-79-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,8,3 and 0 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1187830-79:
(9*1)+(8*1)+(7*8)+(6*7)+(5*8)+(4*3)+(3*0)+(2*7)+(1*9)=190
190 % 10 = 0
So 1187830-79-0 is a valid CAS Registry Number.

1187830-79-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 18, 2017

Revision Date: Aug 18, 2017

1.Identification

1.1 GHS Product identifier

Product name 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one hydrochloride

1.2 Other means of identification

Product number -
Other names 5,6,7,8-Tetrahydropyrido[4,3-d]pyrimidin-4(3H)-one HCl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1187830-79-0 SDS

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