1187890-75-0Relevant academic research and scientific papers
Synthesis and enzymatic evaluation of novel partially fluorinated thiol dual ACE/NEP inhibitors
Olimpieri, Francesca,Tambaro, Simone,Fustero, Santos,Lazzari, Paolo,Sanchez-Rosello, Maria,Pani, Luca,Volonterio, Alessandro,Zanda, Matteo
supporting information; experimental part, p. 4715 - 4719 (2010/04/28)
A novel family of peptidomimetics incorporating fluoroalkyl groups, mainly a trifluoromethyl, in α-position to a zinc(II)-binding thiol function, was synthesized in solution as well as in solid-phase. These compounds showed inhibitory potency in the nanom
