1187890-84-1

Basic information

• Product Name: methyl (E)-(4,4,5,5,5-pentafluoropent-2-enoyl)-L-phenylalaninate
• Synonyms: methyl (E)-(4,4,5,5,5-pentafluoropent-2-enoyl)-L-phenylalaninate
• CAS NO: 1187890-84-1
• Molecular Weight: 351.273
• Mol File: 1187890-84-1.mol

Chemical Properties

• CAS DataBase Reference: methyl (E)-(4,4,5,5,5-pentafluoropent-2-enoyl)-L-phenylalaninate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl (E)-(4,4,5,5,5-pentafluoropent-2-enoyl)-L-phenylalaninate(1187890-84-1)
• EPA Substance Registry System: methyl (E)-(4,4,5,5,5-pentafluoropent-2-enoyl)-L-phenylalaninate(1187890-84-1)

Safety Data

• Hazardous Substances Data: 1187890-84-1(Hazardous Substances Data)

Upstream product

• 108-31-6 maleic anhydride 
• 354-64-3 Pentafluoroethyl iodide 
• 2577-90-4 methyl (2S)-2-amino-3-phenylpropanoate 
• 1187890-79-4 C₅H₂ClF₅O 
• 7524-50-7 methyl (2S)-2-amino-3-phenylpropanoate hydrochloride 

Downstream Products

• 1187890-90-9 C₁₇H₁₈F₅NO₄S 

Relevant articles and documents

Photoinduced Decarboxylative Amino-Fluoroalkylation of Maleic Anhydride

A photoinduced decarboxylative three-component coupling reaction involving amine, maleic anhydride, and fluorinated alkyl iodides has been developed, leading to synthetically valuable fluoroalkyl-containing acrylamides with a high E selectivity. A broad array of substrates including monoprotected amino acid are capable coupling partners. Preliminary mechanistic studies suggest a stepwise process. This reaction represents the first example of photoinduced decarboxylative difunctionalization of maleic anhydride.

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