118791-14-3

Basic information

• Product Name: 6-chloroquinoline-3-carboxylic acid
• Synonyms: 6-chloroquinoline-3-carboxylic acid;3-Carboxy-6-chloroquinoline;6-Chloro-3-quinolinecarboxylic acid
• CAS NO: 118791-14-3
• Molecular Formula: C₁₀H₆ClNO₂
• Molecular Weight: 207.62
• Product Categories: CHIRAL CHEMICALS
• Mol File: 118791-14-3.mol
• Article Data: 2

Chemical Properties

• Melting Point: 228 °C(Solv: ethanol (64-17-5))
• Boiling Point: 382.122 °C at 760 mmHg
• Flash Point: 184.901 °C
• Appearance: /
• Density: 1.47 g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.69
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 2.02±0.30(Predicted)
• CAS DataBase Reference: 6-chloroquinoline-3-carboxylic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloroquinoline-3-carboxylic acid(118791-14-3)
• EPA Substance Registry System: 6-chloroquinoline-3-carboxylic acid(118791-14-3)

Safety Data

• Hazard Codes: Xn
• Statements: 22
• WGK Germany: 3
• Hazardous Substances Data: 118791-14-3(Hazardous Substances Data)

Usage

General Description

6-Chloroquinoline-3-carboxylic acid is a chemical compound with the molecular formula C10H6ClNO2. It is a chlorinated derivative of quinoline, which is a heterocyclic aromatic compound. This chemical is used in the synthesis of pharmaceuticals and agrochemicals, particularly in the production of antimalarial drugs and insecticides. It is also used as an intermediate in the manufacturing of various other organic compounds.6-Chloroquinoline-3-carboxylic acid is a yellow crystalline solid that is sparingly soluble in water and soluble in organic solvents. It is important to handle this compound with care due to its potential health hazards and environmental impact.

InChI:InChI=1/C10H6ClNO2/c11-8-1-2-9-6(4-8)3-7(5-12-9)10(13)14/h1-5H,(H,13,14)

Upstream product

• 375854-57-2 6-chloroquinoline-3-carboxylic acid ethyl ester 
• 40131-09-7 diethyl methoxymethylenemalonate 
• 106-47-8 4-chloro-aniline 

Downstream Products

• 118791-30-3 7-Benzyl-10-chlor-3,4,7,11b-tetrahydro-4-methyl-2H-1,4-diazepino<6,5-c>chinolin-2,5(1H)-dion 
• 118791-36-9 7-Benzyl-10-chlor-3,4-dihydro-4-methyl-2H-1,4-diazepino<6,5-c>chinolin-2,5(7H)-dion 

Relevant articles and documents

Chemical compounds

Provided herein are novel and useful compounds having a tryptase inhibition activity, pharmaceutical compositions comprising such compounds, and methods treating subjects suffering from a condition, disease, or disorder that can be ameliorated by the administration of an inhibitor of tryptase, e.g., asthma and inflammatory diseases, to name only a few.