118793-56-9

Upstream product

• 118793-55-8 4'-benzyloxy-2'-hydroxy-3,4,5'-trimethoxychalkone 
• 120-14-9 3,4-dimethoxy-benzaldehyde 
• 34176-18-6 1-(4-(benzyloxy)-2-hydroxy-5-methoxyphenyl)ethan-1-one 

Downstream Products

• 118793-57-0 7-hydroxy-6,3',4'-trimethoxyflavone 
• 118793-58-1 7-acetoxy-6,3',4'-trimethoxyflavone 

Relevant academic research and scientific papers

Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease

PCT No. PCT/KR97/00144 Sec. 371 Date Jan. 14, 1999 Sec. 102(e) Date Jan. 14, 1999 PCT Filed Jul. 25, 1997 PCT Pub. No. WO98/04541 PCT Pub. Date Feb. 5, 1998The present invention relates to novel flavone/flavanone compounds or their pharmaceutically acceptable salts and process for preparation thereof for protecting gastrointestinal tracts against gastritis, ulcers and inflammatory bowel disease.

Synthesis of Premtorin and Its Isomers

The formulation of Premtorin, a tetraoxygenated flavone isolated from Abrus precatorius, as 3'-hydroxy-6,7,4'-trimethoxyflavone (I) has been confirmed by an unambiguous synthesis.Syntheses of isomeric flavones, viz. 4'-hydroxy-6,7,3'-trimethoxyflavone (II