1187931-39-0 Usage
Description
3-(4-Bromophenyl)pyrrolidine hydrochloride, with the chemical formula C10H12BrNO·HCl and CAS number 1187931-39-0, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceuticals and bioactive molecules. Its unique structure, featuring a bromophenyl group attached to a pyrrolidine ring, allows for versatile chemical modifications and functionalization, making it a valuable building block in medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
3-(4-Bromophenyl)pyrrolidine hydrochloride is used as a key intermediate in the synthesis of pyrazolopyrimidines, which are a class of compounds with significant therapeutic potential. These pyrazolopyrimidines are being actively investigated for their ability to target and modulate the activity of ALK2, a receptor involved in various signaling pathways related to cellular growth, differentiation, and survival.
Used in Medicinal Chemistry Research:
As a versatile reagent, 3-(4-Bromophenyl)pyrrolidine hydrochloride is employed in the development of novel therapeutic agents for the treatment and prevention of ALK2-mediated diseases. Its presence in the molecular structure of pyrazolopyrimidines allows for the fine-tuning of their biological activity, selectivity, and pharmacokinetic properties, which are essential for the discovery of effective and safe drugs.
Used in Drug Discovery and Development:
3-(4-Bromophenyl)pyrrolidine hydrochloride plays a critical role in the design and optimization of new drugs targeting ALK2-mediated diseases. Its unique structural features enable the exploration of different chemical modifications and the generation of diverse pyrazolopyrimidine derivatives with improved potency, selectivity, and pharmacological properties. This contributes to the advancement of drug candidates with the potential to treat a range of diseases, including cancer, fibrosis, and inflammatory disorders, where ALK2 signaling plays a significant role.
Check Digit Verification of cas no
The CAS Registry Mumber 1187931-39-0 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,7,9,3 and 1 respectively; the second part has 2 digits, 3 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1187931-39:
(9*1)+(8*1)+(7*8)+(6*7)+(5*9)+(4*3)+(3*1)+(2*3)+(1*9)=190
190 % 10 = 0
So 1187931-39-0 is a valid CAS Registry Number.