1187954-57-9

Basic information

• Product Name: 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid
• Synonyms: 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid;Fexofenadine EP Impurity G;BRVDCQYIFNJGSU-UHFFFAOYSA-N;Fexofenadine hydrochloride impurity G (EP)
• CAS NO: 1187954-57-9
• Molecular Formula: C32H37NO3
• Molecular Weight: 483.64108
• Mol File: 1187954-57-9.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 681.4±55.0 °C(Predicted)
• Appearance: /
• Density: 1.144±0.06 g/cm3(Predicted)
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility: DMSO (Slightly), Methanol (Slightly)
• PKA: 4.43±0.10(Predicted)
• CAS DataBase Reference: 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid(1187954-57-9)
• EPA Substance Registry System: 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic Acid(1187954-57-9)

Safety Data

• Hazardous Substances Data: 1187954-57-9(Hazardous Substances Data)

Usage

Description

2-(4-(4-(4-(Diphenylmethylene)piperidin-1-yl)-1-hydroxybutyl)phenyl)-2-methylpropanoic acid, also known as 4-[4-[4-(Diphenylmethylene)-1-piperidinyl]-1-hydroxybutyl]-α,α-dimethyl-benzeneacetic acid, is a chemical compound with a complex structure. It is characterized by its diphenylmethylene and piperidinyl groups, as well as its hydroxybutyl and phenyl moieties. 2-(4-(4-(4-(Diphenylmethylene)piperidin-1-yl)-1-hydroxybutyl)phenyl)-2-methylpropanoic acid is known for its role as an impurity in the pharmaceutical industry.

Uses

Used in Pharmaceutical Industry:
2-(4-(4-(4-(Diphenylmethylene)piperidin-1-yl)-1-hydroxybutyl)phenyl)-2-methylpropanoic acid is used as an impurity in the synthesis of fexofenadine (F322490), which is the active metabolite of Terfenadine (T114500). Terfenadine is a H1-histamine receptor antagonist, commonly used to treat allergic symptoms such as sneezing, itching, and runny nose. The presence of this compound as an impurity is significant because it can affect the purity and efficacy of the final pharmaceutical product.