1187964-14-2

Basic information

• Product Name: ethyl 3-{1,4-dioxaspiro[4.5]decan-8-yl}propanoate
• Synonyms: ethyl 3-{1,4-dioxaspiro[4.5]decan-8-yl}propanoate
• CAS NO: 1187964-14-2
• Molecular Weight: 242.315
• Mol File: 1187964-14-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 324.4±17.0 °C(Predicted)
• Density: 1.08±0.1 g/cm3(Predicted)
• CAS DataBase Reference: ethyl 3-{1,4-dioxaspiro[4.5]decan-8-yl}propanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 3-{1,4-dioxaspiro[4.5]decan-8-yl}propanoate(1187964-14-2)
• EPA Substance Registry System: ethyl 3-{1,4-dioxaspiro[4.5]decan-8-yl}propanoate(1187964-14-2)

Safety Data

• Hazardous Substances Data: 1187964-14-2(Hazardous Substances Data)

Upstream product

• 1187964-13-1 (E)-ethyl 3-(1,4-dioxaspiro[4.5]decan-8-yl)acrylate 
• 3618-03-9 methyl 4-hydroxycyclohexanecarboxylate 
• 3685-22-1 4-hydroxycyclohexanecarboxylic acid 
• 6297-22-9 4-carbomethoxycyclohexanone 
• 26845-47-6 methyl 1,4-dioxaspiro[4.5]decane-8-carboxylate 
• 23521-81-5 (1,4-dioxaspiro[4.5]dec-8-yl)methanol 
• 93245-98-8 1,4-dioxaspiro[4.5]decane-8-carbaldehyde 

Downstream Products

• 58012-66-1 3-(4-oxocyclohexyl)propionic acid ethyl ester 

Relevant articles and documents

DEGRADATION OF BRUTON'S TYROSINE KINASE (BTK) BY CONJUGATION OF BTK INIDBITORS WITH E3 LIGASE LIGAND AND METHODS OF USE

Disclosed herein are novel bifunctional compounds formed by conjugating BTK inhibitor moieties with E3 ligase Ligand moieties, which function to recruit targeted proteins to E3 ubiquitin ligase for degradation, and methods of preparation and uses thereof.

Substituted Sulfonamide Compounds

Substituted sulfonamide compounds corresponding to the formula I: processes for the preparation thereof, pharmaceutical composition containing these compounds and the use of substituted sulfonamide compounds for the preparation of pharmaceutical compositions.