1187976-16-4

Basic information

• Product Name: 3,5-diamino-N-((R)-1-(4-fluorophenyl)ethyl)benzamide
• Synonyms: 3,5-diamino-N-((R)-1-(4-fluorophenyl)ethyl)benzamide
• CAS NO: 1187976-16-4
• Molecular Weight: 273.31
• Mol File: 1187976-16-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5-diamino-N-((R)-1-(4-fluorophenyl)ethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5-diamino-N-((R)-1-(4-fluorophenyl)ethyl)benzamide(1187976-16-4)
• EPA Substance Registry System: 3,5-diamino-N-((R)-1-(4-fluorophenyl)ethyl)benzamide(1187976-16-4)

Safety Data

• Hazardous Substances Data: 1187976-16-4(Hazardous Substances Data)

Upstream product

• 535-87-5 3.5-diaminobenzoic acid 
• 374898-01-8 (R)-1-(4-fluorophenyl)ethylamine 

Downstream Products

• 1187976-13-1 3-amino-N-[(R)-1-(4-fluorophenyl)ethyl]-5-methanesulfonylaminobenzamide 

Relevant articles and documents

Design and synthesis of BACE-1 inhibitors utilizing a tertiary hydroxyl motif as the transition state mimic

Two series of drug-like BACE-1 inhibitors with a shielded tertiary hydroxyl as transition state isostere have been synthesized. The most potent inhibitor exhibited a BACE-1 IC50 value of 0.23 μM.