1188-11-0

Basic information

• Product Name: Diethyl ketone oxime
• Synonyms: 3-Pentanone oxime;Diethyl ketone oxime;Pentane-3-oneoxime
• CAS NO: 1188-11-0
• Molecular Formula: C₅H₁₁NO
• Molecular Weight: 101.14694
• Mol File: 1188-11-0.mol
• Article Data: 19

Chemical Properties

• Boiling Point: 166.6°C at 760 mmHg
• Flash Point: 78°C
• Appearance: /
• Density: 0.89g/cm³
• Vapor Pressure: 0.889mmHg at 25°C
• Refractive Index: 1.429
• CAS DataBase Reference: Diethyl ketone oxime(CAS DataBase Reference)
• NIST Chemistry Reference: Diethyl ketone oxime(1188-11-0)
• EPA Substance Registry System: Diethyl ketone oxime(1188-11-0)

Safety Data

• Hazardous Substances Data: 1188-11-0(Hazardous Substances Data)

Usage

InChI:InChI=1/C5H11NO/c1-3-5(4-2)6-7/h7H,3-4H2,1-2H3

Upstream product

• 919-13-1 3-chloro-3-nitroso-pentane 
• 75-24-1 trimethylaluminum 
• 137946-62-4 3,3-dinitropentane 
• 96-22-0 pentan-3-one 
• 546-88-3 acetylhydroxamic acid 
• 1809-10-5 3-bromopentane 
• 616-24-0 3-aminopentane 
• 551-88-2 3-nitropentane 
• 107093-03-8 3-Hydroxyamino-pentan-3-ol 
• 117132-55-5 3,4-diethyl-3,4-dinitrohexane 
• 109-66-0 pentane 

Downstream Products

• 34694-09-2 C₁₄H₁₉N₂O₂PS 
• 53443-29-1 C₁₃H₁₅Cl₂NO₃ 
• 61706-71-6 N-(1-ethylpropylideneaminooxymethyl)-2,6-diethyl-3-(β-methylthioethyl)-α-chloroacetanilide 
• 551-88-2 3-nitropentane 
• 1033750-79-6 C₁₁H₁₃NO 
• 1161512-22-6 C₁₆H₂₃NO₂ 
• 1258876-24-2 4-(pentan-3-ylideneaminooxy)-6-phenylhexan-2-one 
• 6841-84-5 C₈H₁₃NO 
• 1258876-18-4 C₁₃H₁₇NO₂ 
• 75392-04-0 bis(diethylketoximato)triphenylantimony(V) 
• 110590-81-3 N,N'-bis(1-ethylpropyl)-3,4:9,10-perylenebis(dicarboximide) 
• 96-22-0 pentan-3-one 
• 5396-75-8 pentan-3-one-(O-phenylcarbamoyl oxime ) 

Relevant articles and documents

Copper-Catalyzed Annulation of Oxime Acetates with α-Amino Acid Ester Derivatives: Synthesis of 3-Sulfonamido/Imino 4-Pyrrolin-2-ones

A copper-catalyzed annulation of oxime acetates and α-amino acid ester derivatives for the easy preparation of 4-pyrrolin-2-ones bearing a 3-amino group has been developed. This process features the oxidation of amines with oxime esters as the internal oxidant to produce the active 1,3-dinucleophilic and 1,2-dielectrophilic species concurrently. The subsequent nucleophilic cyclization realizes the efficient construction of 4-pyrrolin-2-one derivatives.

Copper-catalyzed synthesis of thiazol-2-yl ethers from oxime acetates and xanthates under redox-neutral conditions

A novel copper-catalyzed annulation of oxime acetates and xanthates for the synthesis of thiazol-2-yl ethers with remarkable regioselectivity has been developed. Various oxime acetates, whether derived from aryl ketones or alkyl ketones, or natural product cores are suitable for this conversion. Unique dihydrothiazoles were also obtained when both reaction sites were methine. Mechanistic studies indicated that imino copper(iii) intermediates were involved. In addition, this protocol proceeded under redox-neutral conditions and did not require additives or ligands.

ANTIVIRAL OXIME PHOSPHORAMIDE COMPOUNDS

Compounds of Formula I: I and their pharmaceutically acceptable salts are useful for the inhibition of HIV reverse transcriptase. The compounds may also be useful for the prophylaxis or treatment of infection by HIV and in the prophylaxis, delay in the onset or progression, and treatment of AIDS. The compounds and their salts can be employed as ingredients in pharmaceutical compositions, optionally in combination with other antiviral agents, immunomodulators, antibiotics or vaccines.