1188266-14-9 Usage
Description
Nifedipine-d6 is intended for use as an internal standard for the quantification of nifedipine by GC- or LC-MS. Nifedipine is a dihydropyridine L-type calcium channel blocker that reduces the amplitude of spontaneous contractions in isolated rabbit ileum when used at a concentration of 1 μM. Nifedipine (1 μM) reduces TGF-β-induced calcium oscillations in human fibroblasts and prevents impairment of lung function in a mouse model of pulmonary fibrosis induced by bleomycin when administered at a dose of 10 mg/kg per day. It also reduces increases in mean arterial blood pressure induced by angiotensin II in spontaneously hypertensive rats when administered at a dose of 10 μg/kg. Formulations containing nifedipine have been used in the treatment of hypertension and angina.
Chemical Properties
Yellow Solid
Uses
Different sources of media describe the Uses of 1188266-14-9 differently. You can refer to the following data:
1. Used as an antihypertensive and antianginal. A labelled dihydorpyridine calcium channel blocker
2. (Nifedipine-d6) Labeled Nifedipine, intended for use as an internal standard for the quantification of Nifedipine by GC- or LC-mass spectrometry.
3. Used as an antihypertensive and antianginal. A labelled dihydorpyridine calcium channel blocker.
Check Digit Verification of cas no
The CAS Registry Mumber 1188266-14-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,8,2,6 and 6 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1188266-14:
(9*1)+(8*1)+(7*8)+(6*8)+(5*2)+(4*6)+(3*6)+(2*1)+(1*4)=179
179 % 10 = 9
So 1188266-14-9 is a valid CAS Registry Number.
