1188276-71-2Relevant academic research and scientific papers
Piperazinyl-glutamate-pyridines as potent orally bioavailable P2Y12 antagonists for inhibition of platelet aggregation
Parlow, John J.,Burney, Mary W.,Case, Brenda L.,Girard, Thomas J.,Hall, Kerri A.,Hiebsch, Ronald R.,Huff, Rita M.,Lachance, Rhonda M.,Mischke, Deborah A.,Rapp, Stephen R.,Woerndle, Rhonda S.,Ennis, Michael D.
scheme or table, p. 4657 - 4663 (2010/04/28)
Polymer-assisted solution-phase (PASP) parallel library synthesis was used to discover a piperazinyl-glutamate-pyridine as a P2Y12 antagonist. Exploitation of this lead provided compounds with excellent inhibition of platelet aggregation as mea
