1188383-77-8

Basic information

• Product Name: 2-(4-(trifluoromethyl)cyclohexyl)acetic acid ethyl ester
• Synonyms: 2-(4-(trifluoromethyl)cyclohexyl)acetic acid ethyl ester
• CAS NO: 1188383-77-8
• Molecular Weight: 238.25
• Mol File: 1188383-77-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2-(4-(trifluoromethyl)cyclohexyl)acetic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(4-(trifluoromethyl)cyclohexyl)acetic acid ethyl ester(1188383-77-8)
• EPA Substance Registry System: 2-(4-(trifluoromethyl)cyclohexyl)acetic acid ethyl ester(1188383-77-8)

Safety Data

• Hazardous Substances Data: 1188383-77-8(Hazardous Substances Data)

Upstream product

• 803736-45-0 2-(4-(trifluoromethyl)cyclohexylidene)acetic acid ethyl ester 
• 75091-99-5 4-(trifluoromethyl)cyclohexan-1-one 

Relevant articles and documents

Nitrogen-containing bicyclic compounds and preparation method and use thereof

The present invention relates to nitrogen-containing bicyclic compounds and a preparation method and use thereof. The compounds or pharmaceutical compositions can be used as an inhibitor of retinoic acid-related orphan receptor gamma t (ROR gamma t). The invention also relates to the preparation method of the compounds and pharmaceutical compositions, and use of the in the compounds and pharmaceutical compositions in treatment or prevention of RORyt-mediated inflammatation or autoimmune diseases in mammals, particularly humans.

SUBSTITUTED ARYL PYRIMIDINONE DERIVATIVES

Substituted aryl pyrimidinone derivatives are provided, of the Formula: wherein variables are as described herein. Such compounds are ligands that may be used to modulate specific receptor activity in vivo or in vitro, and are particularly useful in the treatment of conditions associated with pathological receptor activation in humans, domesticated companion animals and livestock animals. Pharmaceutical compositions and methods for using such compounds to treat such disorders are provided, as are methods for using such ligands for receptor localization studies.