1188417-82-4

Basic information

• Product Name: 4-bromo-3-ethynylaniline
• Synonyms: 4-bromo-3-ethynylaniline
• CAS NO: 1188417-82-4
• Molecular Weight: 196.046
• Mol File: 1188417-82-4.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-bromo-3-ethynylaniline(CAS DataBase Reference)
• NIST Chemistry Reference: 4-bromo-3-ethynylaniline(1188417-82-4)
• EPA Substance Registry System: 4-bromo-3-ethynylaniline(1188417-82-4)

Safety Data

• Hazardous Substances Data: 1188417-82-4(Hazardous Substances Data)

Upstream product

• 54060-30-9 3-acetylenephenylamine 
• 615-55-4 3,4-dibromoaniline 

Relevant articles and documents

Cu-mediated selective bromination of aniline derivatives and preliminary mechanism study

A simple and efficient bromination of aniline, aniline derivatives, and analogs have been developed. Forty three examples were given and the highest yield reached was 98%. Different substrates including substituted aniline, pyridin-amine, N-substituted aniline, N,N-disubstituted aniline, N-phenyl-amide, N-phenyl-sulfonamide, and nitrogen-containing heterocycles were all reactive and selectively generated desired bromo-products. The method can be applied to synthesize drug intermediate and quinoxaline derivatives.