1188477-11-3

Basic information

• Product Name: Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate
• Synonyms: Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate;Carbamic acid, N-[(5-bromo-2-pyridinyl)methyl]-, 1,1-dimethylethyl ester
• CAS NO: 1188477-11-3
• Molecular Formula: C₁₁H₁₅BrN₂O₂
• Molecular Weight: 287.153
• Mol File: 1188477-11-3.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 372.4±32.0 °C(Predicted)
• Appearance: /
• Density: 1.367±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: 11.14±0.46(Predicted)
• CAS DataBase Reference: Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate(1188477-11-3)
• EPA Substance Registry System: Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate(1188477-11-3)

Safety Data

• Hazardous Substances Data: 1188477-11-3(Hazardous Substances Data)

Usage

General Description

Tert-Butyl5-Bromopyridin-2-yl(methyl)carbamate is a chemical compound that likely falls within the field of organic chemistry due to its complicated structure featuring carbamate functional group, a pyridinyl group and a bromine atom. It is not a naturally occurring substance but instead is synthesized in a lab, typically for research purposes or to be used as an intermediate in the production of other complex organic molecules. The specific properties of this chemical, including its physical state, melting point, boiling point, density, and solubility, would depend on its specific synthesis. Similarly, its toxicity and reactivity would also depend on the exact nature of the compound's structure and how it's synthesized.

Upstream product

• 31181-90-5 5-bromo-pyridine-2-carbaldehyde 
• 4248-19-5 tert-butyl carbazate 
• 173999-23-0 C-(5-bromo-pyridin-2-yl)-methylamine 
• 24424-99-5 di-tert-butyl dicarbonate 
• 97483-77-7 2-Cyano-5-bromopyridine 

Downstream Products

• 1241911-26-1 (5-bromopyridin-2-yl)methanamine hydrochloride 
• 173999-23-0 C-(5-bromo-pyridin-2-yl)-methylamine 
• 928648-90-2 (Z)-(5-(2-cyclohexylvinyl)pyridin-2-yl)methanamine 
• 1454904-80-3 2,2-dichloro-N-{(1S,2R)-1-fluoromethyl-2-hydroxy-2-[4-(6-ureidomethylpyridin-3-yl)phenyl]ethyl}acetamide 
• 1454904-54-1 2,2-dichloro-N-((1S,2R)-1-fluoromethyl-2-hydroxy-2-{4-[6-(isopropylaminomethyl)pyridin-3-yl]phenyl}ethyl)acetamide 
• 1454907-21-1 (4S,5R)-4-fluoromethyl-5-{4-[6-(isopropylaminomethyl)pyridin-3-yl]phenyl}-2,2-dimethyloxazolidine-3-carboxylic acid tert-butyl ester 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS AS MODULATORS OF STIMULATOR OF INTERFERON GENES (STING)

The present invention relates to compounds of formula (I) and salts, stereoisomers, tautomers or N-oxides thereof that are useful as modulators of STING (Stimulator of Interferon Genes). The present invention further relates to the compounds of formula (I) for use as a medicament and to a pharmaceutical composition comprising said compounds.

INHIBITORS OF ECTONUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE 1 (ENPP1) AND METHODS OF USE THEREOF

Compounds and methods for their preparation and use as therapeutic or prophylactic agents, for example for treatment of cancer, bacterial or viral diseases by targeting Ectonucleotide Pyrophosphatase/Phosphodiesterase-1 (ENPP1).

Z-Selective Synthesis of Vinyl Boronates through Fe-Catalyzed Alkyl Radical Addition

Z-Selective synthesis of vinyl boronates is challenging. This work describes Fe-catalyzed addition of alkyl radicals, formed by the corresponding alkyl halides, to ethynyl ethynylboronic acid pinacol ester that gives rise to Z-vinyl boronates in high ster