118849-61-9

Basic information

• Product Name: 3-trifluoromethylphenyl sulfinic acid sodium salt
• Synonyms: 3-trifluoromethylphenyl sulfinic acid sodium salt
• CAS NO: 118849-61-9
• Molecular Weight: 232.159
• Mol File: 118849-61-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: 3-trifluoromethylphenyl sulfinic acid sodium salt(CAS DataBase Reference)
• NIST Chemistry Reference: 3-trifluoromethylphenyl sulfinic acid sodium salt(118849-61-9)
• EPA Substance Registry System: 3-trifluoromethylphenyl sulfinic acid sodium salt(118849-61-9)

Safety Data

• Hazardous Substances Data: 118849-61-9(Hazardous Substances Data)

Upstream product

• 777-44-6 3-(Trifluoromethyl)benzenesulfonyl chloride 

Downstream Products

• 41142-04-5 (3-Phenyl-propoxycarbonylamino)-(3-trifluoromethyl-benzenesulfonyl)-acetic acid 
• 937-00-8 3-trifluoromethyl-thiophenol 
• 2402-03-1 3-trifluoromethylphenyl thiocyanate 
• 118591-71-2 α-3-trifluoromethylphenylsulphonyl-2,6-difluorobenzaldoxime 
• 1078630-64-4 1,3,7-trimethyl-8-(3-(trifluoromethyl)phenyl)-xanthine 
• 1287295-93-5 C₂₆H₂₇F₃N₂O₄S 
• 1287293-45-1 C₂₁H₁₉F₃N₂O₂S*ClH 
• 1416007-20-9 (7S,10R)-tert-butyl 5-methyl-2-((3-(trifluoromethyl)phenyl)sulfonyl)-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]indole-11-carboxylate 
• 1416007-22-1 (7R,10S)-tert-butyl 5-methyl-2-((3-(trifluoromethyl)phenyl)-sulfonyl)-5,6,7,8,9,10-hexahydro-7,10-epiminocyclohepta[b]-indole-11-carboxylate 
• 682786-14-7 N-phenyl-3-(trifluoromethyl)benzenesulfonamide 

Relevant articles and documents

Enhancing the Potential of Miniature-Scale DNA-Compatible Radical Reactions via an Electron Donor-Acceptor Complex and a Reversible Adsorption to Solid Support Strategy

DNA-encoded library (DEL) technology is a powerful tool in the discovery of bioactive probe molecules and drug leads. Mostly, the success in DEL technology stems from the molecular diversity of the chemical libraries. However, the construction of DELs has been restricted by the idiosyncratic needs and the required low concentration (～1 mM or less) of the library intermediate. Here, we report visible-light-promoted on-DNA radical coupling reactions via an electron donor-acceptor (EDA) complex and a reversible adsorption to solid support (RASS) strategy. This protocol provides a unique solution to the challenges of increasing the reactivity of highly diluted DNA substrates and reducing the residues of heavy metals from photocatalysts. A series of on-DNA indole sulfone and selenide derivatives were obtained with good to quantitative conversions. It is anticipated that these mild-condition on-DNA radical reactions will significantly improve the chemical diversity of DELs and find widespread utility to DEL construction.

Sulfonamide formation from sodium sulfinates and amines or ammonia under metal-free conditions at ambient temperature

A novel, practical and highly efficient method for the construction of a variety of sulfonamides mediated by I2 was demonstrated. The reaction proceeds readily at room temperature using a variety of sodium sulfinates and amines or ammonia in water in a metal-, base-, ligand-, or additive-free protocol. Primary, secondary and tertiary sulfonamides were obtained in good to excellent yields with a broad range of functional group tolerability. This journal is

BENZOFURO[3,2-c] PYRIDINES AND RELATED ANALOGS AS SEROTONIN SUB-TYPE 6 (5-HT6) MODULATORS FOR THE TREATMENT OF OBESITY, METABOLIC SYNDROME, COGNITION AND SCHIZOPHRENIA

The present invention relates to benzofuro[3,2-c]pyridine and azepine analogs as serotonin sub-type 6 (5-HT6) modulators, pharmaceutical compositions including these compounds, methods of preparation, and use thereof. These compounds are useful in the treatment of central nervous system disorders including obesity, metabolic syndrome, cognition, schizophrenia, attention deficit hyperactivity disorder, bipolar disorder, rare and orphan diseases, and sleep disorders. The subject compounds have the structure of formula (I) with the substituents being described herein.