1188499-13-9Relevant articles and documents
Facile and convenient strategy towards synthesis of 4-substituted 2-aminothiazolo[4,5-d]pyridazinones
Thorave, Amol A.,Prajapati, Pinkal N.,Pethani, Jignesh P.,Kothari, Krunal C.,Jain, Mukul R.,Patel, Pankaj R.,Kharul, Rajendra K.
supporting information; scheme or table, p. 5660 - 5663 (2011/02/24)
Convenient synthesis of 4-substituted 2-aminothiazolo[4,5-d]pyridazinones has been achieved in 12 steps with overall yield of 19% by employing Grignard reaction as the key step. The route utilizes well established thiazole ring formation followed by Grign