1188522-42-0Relevant articles and documents
OLIGONUCLEOTIDE-LIGAND CONJUGATES AND PROCESS FOR THEIR PREPARATION
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Page/Page column 146; 147; 150; 151, (2015/02/02)
The present invention relates to ligand conjugates of oligonucleotides (e.g., iRNA agents) and methods for their preparation. The ligands are derived primarily from monosaccharides These conjugates are useful for the in vivo delivery of oligonucleotides.
NON-NATURAL RIBONUCLEOTIDES, AND METHODS OF USE THEREOF
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Page/Page column 113, (2009/10/22)
One aspect of the present invention relates to modified nucleosides and oligonucleotides comprising such modified nucleosides. Another aspect of the invention relates to a method of inhibiting the expression of a gene in call, the method comprising (a) co