1188945-12-1 Usage
General Description
1-(3,4,5-Trifluorophenyl)-1H-pyrrole-2,5-dione is a chemical compound with the molecular formula C10H4F3NO2. It is a pyrrole-2,5-dione derivative with a trifluorophenyl group attached to the pyrrole ring. 1-(3,4,5-Trifluorophenyl)-1H-pyrrole-2,5-dione has potential applications in the field of medicinal chemistry and pharmaceuticals due to its unique structure and potential therapeutic properties. It may have biological activities such as anticancer, antifungal, and antibacterial properties, making it a subject of interest for further study. Additionally, it may have uses in the development of new drug candidates and as a building block for organic synthesis in chemical research.
Check Digit Verification of cas no
The CAS Registry Mumber 1188945-12-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,8,9,4 and 5 respectively; the second part has 2 digits, 1 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1188945-12:
(9*1)+(8*1)+(7*8)+(6*8)+(5*9)+(4*4)+(3*5)+(2*1)+(1*2)=201
201 % 10 = 1
So 1188945-12-1 is a valid CAS Registry Number.
1188945-12-1Relevant articles and documents
Unusual regio- and stereo-selectivity in Diels-Alder reactions between bulky N-phenylmaleimides and anthracene derivatives
Chen, Hao,Yao, Erdong,Xu, Chi,Meng, Xiao,Ma, Yuguo
supporting information, p. 5102 - 5107 (2014/07/08)
Unusual regio- and stereo-selectivity in Diels-Alder (D-A) reactions were achieved between bulky N-phenylmaleimides and anthracene derivatives. Using multiple substituents with steric hindrance on both diene and dienophile, a noticeable shift toward 1,4-addition was successfully obtained. The substrate scope in this reaction was broad and the highest yield of anti-1,4-adducts was over 90%. Novel structures of anti-1,4-adducts were confirmed by single crystal X-ray diffraction analysis. This study not only provides the first reported method of synthesizing anti-1,4-adducts and achieving otherwise unattainable regio- and stereo-selectivity, but also elucidates the importance of combining the steric effects of two reactants to shift products toward 1,4-adducts. Moreover, the resulting 1,4-adducts could be further functionalized through their halogen groups via carbon-carbon coupling reactions.