1189160-74-4Relevant academic research and scientific papers
Chromane derivatives of small aromatic molecules: Chemoenzymatic synthesis and growth inhibitory activity on human tumor cell line LoVo WT
Macone, Alberto,Lendaro, Eugenio,Comandini, Alessandra,Rovardi, Irene,Matarese, Rosa Marina,Carraturo, Antonio,Bonamore, Alessandra
, p. 6003 - 6007 (2009)
Aromatic substrates tyrosol (p-hydroxyphenylethanol) and 2,6-dihydroxynaphthalene (2,6-DHN) were converted into chromane derivatives by means of chemoenzymatic reactions catalyzed by the aromatic prenyltransferase of bacterial origin NovQ, using dimethyla
Butenolide derivative as well as preparation method and application thereof
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Paragraph 0052-0055, (2020/07/21)
The invention discloses a butenolide compound as well as a preparation method and an application thereof. The butenolide derivative has the inhibitory activity of protein tyrosine phosphatase 1B (PTP1B), improves insulin resistance of HepG2 cells, generates a remarkable hypoglycemic effect and can be used for preparing a medicine for treating diabetes mellitus.
