Cas 1189178-08-2,1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide

1189178-08-2

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Basic information

Product Name: 1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide
Synonyms: 1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide
CAS NO:1189178-08-2
Molecular Formula:
Molecular Weight: 494.91
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide(CAS DataBase Reference)
NIST Chemistry Reference: 1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide(1189178-08-2)
EPA Substance Registry System: 1-(3-chloro-4-fluorophenyl)-6-methyl-N-(4-methylphenyl)-4-(3-nitrophenyl)-3,4-dihydropyrimidin-2(1H)-one-5-carboxamide(1189178-08-2)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1189178-08-2(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1189178-08-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,1,7 and 8 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 1189178-08:
(9*1)+(8*1)+(7*8)+(6*9)+(5*1)+(4*7)+(3*8)+(2*0)+(1*8)=192
192 % 10 = 2
So 1189178-08-2 is a valid CAS Registry Number.

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1189178-08-2Relevant academic research and scientific papers

Multi-component synthesis of dihydropyrimidines by iodine catalyst at ambient temperature and in-vitro antimycobacterial activity

Zalavadiya, Paresh,Tala, Satish,Akbari, Jignesh,Joshi, Hitendra

experimental part, p. 469 - 475 (2009/12/05)

An efficient and simple three-component domino synthesis of some new dihydropyrimidines (DHPMs) from aromatic aldehydes, 1,3-dicarbonyl compounds and N-(3-chloro-4-fluorophenyl) urea using molecular iodine as catalyst is described. The 1-substituted dihydropyrimidines were isolated in good to excellent yields (78-90%) within a short reaction time (4-6 h) at ambient temperature. The biological evaluation revealed that the newly synthesized compounds (4a-i and 5a-i) exhibited moderate antimycobacterial activity against Mycobacterium tuberculosis H37 RV.

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