118947-69-6

Upstream product

• 118947-64-1 6-(2-Oxo-2-phenyl-ethylsulfanyl)-[2,3']bipyridinyl-5-carbonitrile 
• 58764-55-9 3-piperidin-1-yl-1-pyridin-3-yl-propenone 
• 39883-42-6 β-oxo-3-pyridinepropanal sodium salt 
• 118947-87-8 6-(pyridine-2-yl)-3-cyanopyridine-2-(1H)-thione 
• 70-11-1 α-bromoacetophenone 

Relevant academic research and scientific papers

Synthesis of some new bipyridines, thieno[2,3-b]pyridines, and pyrazolo[3,4-b]pyridines

Cyclocondensation of cyanoacetamide and cyanothioacetamide with sodium salt of 3-hydroxy-1-(pyridin- 3-yl)prop-2-en-1-one gave 6-oxo-[2,3′]bipyridine 5a and 6-thioxo-[2,3′]bipyridine 5b derivatives, respectively. Compound 5b upon treatment with different methylenes 8 gave thieno[2,3-b]pyridines 10. Treatment of 5b with iodomethane gave bipyridine derivative 7, which cyclocondensed with hydrazines 11 to give pyrazolo[3,4-b]pyridines 13..

CYCLIZATION REACTIONS OF NITRILS. 29. REGIOSELECTIVE SYNTHESIS OF 6-ARYL-3-CYANO-2(1H)-PYRIDINETHIONES AND THE CORRESPONDING SELENONES AND THEIR CHARACTERISTICS

The condensation of cyanothio- and cyanoselenoacetamide with 3-aryl-3-oxo-1-piperidino-1-propene or sodium 3-aryl-3-oxo-1-propen-1-olate takes place regioselectively with the formation of the 6-aryl-3-cyano-2(1H)-pyridinethiones or the corresponding selenones.Thienopyridines, thiazolopyridinium salts, and other annellated heterocycles were obtained from the 6-aryl-3-cyano-2(1H)-pyridinethiones.