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CAS

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1189477-66-4

Nilutamide-d6 is a crystalline solid that serves as an internal standard for the quantification of Nilutamide using gas chromatography (GC) or liquid chromatography (LC) mass spectrometry (MS). Nilutamide is a non-steroidal antiandrogen with antineoplastic (hormonal) properties, acting as an antagonist of the androgen receptor. It is effective in reversing testosterone-induced cell proliferation and has demonstrated antiandrogenic activity in both intact and castrated rats. Nilutamide formulations have been utilized in combination with surgical castration for the treatment of metastatic prostate cancer.

1189477-66-4

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  • 5,5-di(2H )methyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione

    Cas No: 1189477-66-4

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1189477-66-4 Usage

Uses

Used in Pharmaceutical Industry:
Nilutamide-d6 is used as an internal standard for the quantification of Nilutamide in pharmaceutical applications. This aids in the accurate measurement and analysis of Nilutamide, which is a non-steroidal antiandrogen with potential applications in the treatment of metastatic prostate cancer.
Used in Mass Spectrometry:
Nilutamide-d6 is used as an internal standard for GCor LC-MS, ensuring the precision and reliability of Nilutamide measurements. This is crucial for the development and quality control of pharmaceutical formulations containing Nilutamide, as well as for research purposes in understanding its antiandrogenic and antineoplastic properties.
Used in Cancer Research:
Nilutamide-d6 plays a role in cancer research, particularly in the study of Nilutamide's effects on androgen receptor antagonism and its potential use in the treatment of metastatic prostate cancer. As an internal standard, it helps researchers accurately assess the concentration and activity of Nilutamide in various experimental setups, contributing to a better understanding of its therapeutic potential.

Check Digit Verification of cas no

The CAS Registry Mumber 1189477-66-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,4,7 and 7 respectively; the second part has 2 digits, 6 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1189477-66:
(9*1)+(8*1)+(7*8)+(6*9)+(5*4)+(4*7)+(3*7)+(2*6)+(1*6)=214
214 % 10 = 4
So 1189477-66-4 is a valid CAS Registry Number.

1189477-66-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 3-[4-nitro-3-(trifluoromethyl)phenyl]-5,5-bis(trideuteriomethyl)imidazolidine-2,4-dione

1.2 Other means of identification

Product number -
Other names Nilutamide-d6

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:1189477-66-4 SDS

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