1189488-17-2

Basic information

• Product Name: N-Desmethyl Loperamide-d3
• Synonyms: 4-(4-Chlorophenyl)-4-hydroxy-N-(methyl-d3)-a,a-diphenyl-1-piperidinebutanamide;N-Desmethyl Loperamide-d3;R 20905-d3;4-(4-Chlorophenyl)-4-hydroxy-N-(Methyl-d3)-α,α-diphenyl-1-piperidinebutanaMide
• CAS NO: 1189488-17-2
• Molecular Formula: C28H31ClN2O2
• Molecular Weight: 463.01094
• Product Categories: Amines;Heterocycles;Intermediates & Fine Chemicals;Isotope Labeled Compounds;Metabolites & Impurities;Pharmaceuticals;Isotope Labelled Compounds;Heterocycles, Isotope Labelled Compounds, Metabolites & Impurities, Pharmaceuticals, Intermediates & Fine Chemicals
• Mol File: 1189488-17-2.mol
• Article Data: 0

Chemical Properties

• Melting Point: 220-222?C
• Appearance: /
• Storage Temp.: -20°C Freezer
• CAS DataBase Reference: N-Desmethyl Loperamide-d3(CAS DataBase Reference)
• NIST Chemistry Reference: N-Desmethyl Loperamide-d3(1189488-17-2)
• EPA Substance Registry System: N-Desmethyl Loperamide-d3(1189488-17-2)

Safety Data

• Hazardous Substances Data: 1189488-17-2(Hazardous Substances Data)

Usage

Description

N-Desmethyl Loperamide-d3 is a labeled metabolite of Loperamide, which is an off-white solid. It serves as a new and improved PET radiotracer for imaging P-gp function.

Uses

Used in Pharmaceutical Industry:
N-Desmethyl Loperamide-d3 is used as a PET radiotracer for imaging P-gp function, which is crucial for understanding the role of P-gp in drug resistance and absorption. This allows researchers and clinicians to monitor and evaluate the effectiveness of drug therapies and develop new strategies to overcome drug resistance.
Used in Research Applications:
N-Desmethyl Loperamide-d3 is used as a research tool for studying the function and activity of P-gp in various biological systems. This helps researchers gain insights into the mechanisms of drug transport and develop new drugs with improved efficacy and reduced side effects.