1189530-47-9Relevant academic research and scientific papers
Evaluation of spirocyclic 3-(3-fluoropropyl)-2-benzofurans as σ1 receptor ligands for neuroimaging with positron emission tomography
Maestrup, Eva Gro?e,Fischer, Steffen,Wiese, Christian,Schepmann, Dirk,Hiller, Achim,Deuther-Conrad, Winnie,Steinbach, J?rg,Wünsch, Bernhard,Brust, Peter
supporting information; experimental part, p. 6062 - 6072 (2010/03/24)
A series of various N-substituted 3-(3-fluoropropyl)-3H-spiro[[2] benzofuran-1,4′-piperidines] (7) has been synthesized. In receptor binding studies, the N-benzyl derivative 7a (WMS-1813) revealed extraordinarily high σ1 receptor affinity (Ksu
