118958-22-8Relevant academic research and scientific papers
A study of the synthesis and antiarrhythmic properties of selected 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2,4-positions and at the 9-position
Smith,Thompson,Berlin,Holt,Scherlag,Patterson,Lazzara
, p. 1 - 8 (2007/10/02)
Some members of the family of 3,7-diheterabicyclo[3.3.1]nonanes with substituents at the 2-, 4- and 9-positions were synthesized via a Mannich reaction. Hearts of anesthetized dogs with myocardial infarctions were subjected to ventricular tachycardia (VT)
Certain 3-selena-7-aza-bicyclo[3.3.1]nonanes as antiarrhythmic agents
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, (2008/06/13)
3-7-Diheterabicylo[3.3.1]nonanes and derivatives thereof are disclosed. Their method of preparation and use as antiarrhythmic agents is given.
