1189677-14-2 Usage
Description
1'-HYDROXYMIDAZOLAM-13C3 is a labeled metabolite of Midazolam, which is a CYP3A4 labeled metabolite. It is an off-white solid and is used in various applications due to its unique properties.
Uses
Used in Pharmaceutical Industry:
1'-HYDROXYMIDAZOLAM-13C3 is used as a labeled metabolite for the study and analysis of the CYP3A4 enzyme's activity. This is important in understanding the metabolism of certain drugs and their interactions with the enzyme.
Used in Research and Development:
1'-HYDROXYMIDAZOLAM-13C3 is used as a research tool for investigating the role of CYP3A4 in drug metabolism and its implications in drug-drug interactions. This helps in the development of new drugs and the optimization of existing ones.
Used in Quality Control:
1'-HYDROXYMIDAZOLAM-13C3 is used as a reference compound in the quality control of pharmaceutical products, ensuring the accuracy and reliability of analytical methods used in the detection and quantification of Midazolam and its metabolites.
Used in Drug Metabolism Studies:
1'-HYDROXYMIDAZOLAM-13C3 is used as a labeled internal standard in drug metabolism studies, allowing for the accurate measurement of Midazolam and its metabolites in biological samples, such as blood, plasma, or urine.
Check Digit Verification of cas no
The CAS Registry Mumber 1189677-14-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,6,7 and 7 respectively; the second part has 2 digits, 1 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1189677-14:
(9*1)+(8*1)+(7*8)+(6*9)+(5*6)+(4*7)+(3*7)+(2*1)+(1*4)=212
212 % 10 = 2
So 1189677-14-2 is a valid CAS Registry Number.
1189677-14-2Relevant articles and documents
The use of biocatalysis in the synthesis of labelled compounds
Allen, John,Brasseur, Denis M.,De Bruin, Beatrice,Denoux, Mireille,Perard, Serge,Philippe, Nicolas,Roy, Sebastien N.
, p. 342 - 346 (2007)
Since most biotransformations are highly chemo-, regio- and stereoselective, they offer many opportunities for the synthesis of compounds that are not easily attainable by classical organic chemistry, The catalytic properties of the cytochrome P450 (CYP45
