118975-83-0Relevant academic research and scientific papers
STEREOSELECTIVE ONE-POT SYNTHESES OF TRANS-3-AMINO-β-LACTAMS FROM ZINC ENOLATES OF N-PROTECTED α-AMINOACID ESTERS AND IMINES
Steen, Fred H. van der,Jastrzebski, Johann T.B.H.,Koten, Gerard van
, p. 2467 - 2470 (2007/10/02)
A new one-pot synthesis of 3-amino-β-lactams that is based on the condensation of simple imines with zinc enolates of disilyl protected glycine esters is reported.Isolated yields are high and a trans-selectivity is observed.
