1189757-60-5 Usage
General Description
The chemical 6-oxo-5-(trifluoromethyl)-1,6-dihydropyridine-3-carboxylic acid is a dihydropyridine derivative with a trifluoromethyl group attached to the fifth position. It is a carboxylic acid, containing a six-membered ring with an oxygen and nitrogen atom. 6-Oxo-5-(trifluoromethyl)-1,6-dihydropyridine-3-carboxylic acid is often used in pharmaceutical research and drug development due to its potential biological activity and ability to interact with various biological targets. It has been studied for its potential use as a calcium channel antagonist and as a potential treatment for cardiovascular diseases. The trifluoromethyl group may also enhance the compound's biological activity and bioavailability.
Check Digit Verification of cas no
The CAS Registry Mumber 1189757-60-5 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,1,8,9,7,5 and 7 respectively; the second part has 2 digits, 6 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1189757-60:
(9*1)+(8*1)+(7*8)+(6*9)+(5*7)+(4*5)+(3*7)+(2*6)+(1*0)=215
215 % 10 = 5
So 1189757-60-5 is a valid CAS Registry Number.
1189757-60-5Relevant articles and documents
BENZAMIDE DERIVATIVE
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Paragraph 1457; 1458, (2015/03/16)
The present invention relates to benzamide derivatives represented by formula (I) or pharmaceutically acceptable salts thereof.
Discovery of pyridone-containing imidazolines as potent and selective inhibitors of neuropeptide Y Y5 receptor
Ando, Makoto,Sato, Nagaaki,Nagase, Tsuyoshi,Nagai, Keita,Ishikawa, Shiho,Takahashi, Hirobumi,Ohtake, Norikazu,Ito, Junko,Hirayama, Mioko,Mitobe, Yuko,Iwaasa, Hisashi,Gomori, Akira,Matsushita, Hiroko,Tadano, Kiyoshi,Fujino, Naoko,Tanaka, Sachiko,Ohe, Tomoyuki,Ishihara, Akane,Kanatani, Akio,Fukami, Takehiro
experimental part, p. 6106 - 6122 (2009/12/24)
A series of 2-pyridone-containing imidazoline derivatives was synthesized and evaluated as neuropeptide Y Y5 receptor antagonists. Optimization of the 2-pyridone structure on the 2-position of the imidazoline ring led to identification of 1-(difluoromethy
