118977-96-1

Basic information

• Product Name: C₅₆H₉₇NO₁₂Si₂
• Synonyms: C₅₆H₉₇NO₁₂Si₂
• CAS NO: 118977-96-1
• Molecular Weight: 1032.56
• Mol File: 118977-96-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: C₅₆H₉₇NO₁₂Si₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₅₆H₉₇NO₁₂Si₂(118977-96-1)
• EPA Substance Registry System: C₅₆H₉₇NO₁₂Si₂(118977-96-1)

Safety Data

• Hazardous Substances Data: 118977-96-1(Hazardous Substances Data)

Upstream product

• 1896-61-3 methyl-tris(p-toluylphenyl)phosphonium iodide 
• 126789-47-7 C₅₆H₉₉NO₁₂Si₂ 

Downstream Products

• 104987-11-3 Tacrolimus 

Relevant articles and documents

Rapid synthesis of 11C-labeled FK506 for positron emission tomography

The present study describes a rapid synthesis method for labeled [11C]FK506 for positron emission tomography (PET). A one-pot reaction from [11C]CH3I, involving a Wittig reaction as the key carbon-carbon bond formation was developed. The chemical process was accomplished using a designed, fully automated synthetic apparatus, and an injectable solution of [11C]FK506 was obtained in only 34 min from [11C]CH3I. The decay-corrected radiochemical yield based on [11C]CH3I was 11.9%, and the specific activity was 39.8 GBq/μmol.

Total Synthesis of the Immunosuppressant (-)-FK-506

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