1189797-75-8Relevant academic research and scientific papers
Triazoloquinazolinediones as novel high affinity ligands for the benzodiazepine site of GABAA receptors
Nilsson, Jakob,Gidl?f, Ritha,Nielsen, Elsebet ?stergaard,Liljefors, Tommy,Nielsen, Mogens,Sterner, Olov
experimental part, p. 111 - 121 (2011/02/28)
Based on a pharmacophore model of the benzodiazepine-binding site of GABAA receptors, a series of 2-aryl-2,6-dihydro[1,2,4]triazolo[4,3-c] quinazoline-3,5-diones (structure type I) were designed, synthesized, and identified as high-affinity lig
GABAA RECEPTOR MODULATORS
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Page/Page column 14-15; 29, (2009/10/30)
the resent invention relates to novel compounds of the general formula (I) having anxiolytic, anticonvulsant, sedative-hypnotic and myorelaxant conditions as well as anxiogenic, somnolytic and convulsant conditions in mammals, including humans, as GABAA receptor modulator.
