118985-48-1Relevant academic research and scientific papers
Heterocyclic glycerol derivatives and their use as anti-hypertensive agents
-
, (2008/06/13)
A novel glycerol derivative which is effective to reduce blood pressure has the formula: STR1 wherein R1 is an alkyl group having 10-22 carbon atoms, R2 is lower acyl, benzoyl, aryl, mono-, di- or triarylalkyl, alkyl, cycloalkyl, or cycloalkylalkyl; Q is substituted or unsubstituted alkylene containing 1-4 carbon atoms, l is 0 or 1; Y is a nitrogen-containing heterocyclic group or a nitrogen-containing bridged heterocyclic group (--(Q)l -- is attached to a carbon atom contained in a hetero-ring of the heterocyclic group) in which Y is the bridged heterocyclic group where l is 0; and each of R5, R6 and R7 is hydrogen, lower alkyl, aryl or aralkyl.
