118992-07-7

Upstream product

• 66535-64-6 (+/-)-4-trimethylsilylbut-3-en-2-ol 
• 7322-88-5 (S)-acetylmandelic acid 
• 56919-89-2 (2E)-1-(trimethylsilyl)-2-buten-1-ol 
• 133618-98-1 1-(1-trimethylsilyl-2-butene) (2R)-2-O-acetyl-2-phenyl-acetate 

Downstream Products

• 133619-13-3 (3R)-3-(1-trimethylsilyl-1-butene) (2R)-2-hydroxy-2-phenylacetate 
• 133619-12-2 (3S)-3-(1-trimethylsilyl-1-butene) (2R)-2-hydroxy-2-phenylacetate 

Relevant academic research and scientific papers

Synthesis, resolution and absolute stereochemical assignment of C1-oxygenated allylsilanes and C3-oxygenated vinylsilanes

(R)-O-acetyl mandelic acid has been utilized for the development of a procedure for resolution and absolute stereochemical assignment of C1-oxygenated E-crotylsilanes 1a-c. The procedure is enhanced further by an efficient boron trifluoride etherate catal

EPOXY-SILANES IN ORGANIC SYNTHESIS

Stereoselective reactions involving functionalised β,γ-epoxysilanes and epoxide-allylsilanes provide a range of synthetically useful transformations.