118993-61-6Relevant articles and documents
4-Substituted thiophene- and furan-2-sulfonamides as topical carbonic anhydrase inhibitors
Hartman,Halczenko,Smith,Sugrue,Mallorga,Michelson,Randall,Schwam,Sondey
, p. 3822 - 3831 (2007/10/02)
A series of 4-substituted thiophene- and furan-2-sulfonamides was prepared and was found to possess nanomolar-level potency for inhibition of human carbonic anhydrase II in vitro. Selected examples from this group were further evaluated for their potentia
4-(benzoyl)thiophene(or furan)-sulfonamide and derivatives thereof for the topical treatment of elevated intraocular pressures
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, (2008/06/13)
4-(benzoyl)thiophene(or furan)-2-sulfonamide and derivatives thereof are useful for the topical treatment of elevated intraocular pressure.